Covid-19: Arthritis drug trial for severe illness is stopped early after increase in deaths

نویسندگان

چکیده

A trial testing whether the arthritis drug tocilizumab plus standard care could improve outcomes for patients with severe or critical covid-19 has been stopped early after an increase in deaths.1 Just 129 (average age 57; 68% male) had enrolled when data monitoring committee recommended that it should be stopped. This was due to 11 of 65 (17%) group dying by day 15, compared two 64 (3%) only (odds ratio 6.42 (95% confidence interval 1.59 43.2)). The results, published The BMJ ,1 seem contradict earlier observational studies reported a benefit tocilizumab. Recent results from REMAP-CAP showed that, …

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ژورنال

عنوان ژورنال: BMJ

سال: 2021

ISSN: ['0959-8138']

DOI: https://doi.org/10.1136/bmj.n186